Certified Paraoptometric (CPO) Practice Exam 2025

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Which prefix denotes something that is "under" or "below"?

Hypo-, Sub-
Para-
Peri-
Retro-

The correct answer is: Hypo-, Sub-

The prefix that denotes something that is "under" or "below" is indeed a combination of both "hypo-" and "sub-". The prefix "hypo-" is derived from Greek, meaning "under," "below," or "less than normal," while "sub-" comes from Latin, conveying a similar notion of being beneath or below something. These prefixes are commonly used in medical terminology to describe conditions or locations that are lower in position or quantity. For instance, "hypoglycemia" refers to abnormally low levels of glucose in the blood, and "subcutaneous" refers to the tissue located beneath the skin. The other prefixes are associated with different meanings: "para-" typically means "beside" or "around," "peri-" refers to "surrounding" or "around," and "retro-" denotes something that is "backward" or "behind." Thus, they do not convey the same concept of being "under" or "below."